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Talon Biomarkers is a full-service CRO,
offering experimental design, high parameter immune monitoring, and data analysis.

We generate robust, easy-to-interpret results rapidly,
providing maximal insight from minimal sample.






The first report of 17-color flow cytometry.  Talon's founder later reported the first 30-parameter experiment.

nature medicine

17 August 2006

The first report of 17-color flow cytometry.  

journal of immunological methods

1 September 2006

The first report and characterization of today's most popular viability dyes.

nature medicine

25 September 2005

A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles

The first live-cell assay for purification of antigen-specific CD4+ T-cells.

nature protocols

9 November 2006

One of the earliest, most comprehensive quality control systems for polychromatic flow cytometry.

nature methods

31 July 2017

Simultaneous epitope and transcriptome measurements in single cells

The first single-cell sequencing-based method for simultaneous analysis of protein and transcript expression.


22 October 2018

The first 30-parameter flow cytometry panel developed for immuno-oncology. OMIP manuscripts developed by Talon's founder.

paper of the year award

27 July 2021

Single cell multiomic analysis of T cell exhaustion in vitro

In-depth, award-winning profiling of exhausted cells using flow cytometry and AbSeq technology.

Disease Applications

2009 - 2023

Novel immunotherapy SL-701
for recurrent glioblastoma: Prognostic Value of Treatment-Induced CD8+CD57+ T-cells as a Marker for Survival, SNO Oral Presentation, 2024; Clinical Trial Award, 2023.

Lymphomatoid Granulomatosis, Lancet Haematology, 2023.

Tumor-infiltrating lymphocytes in hepatic and pancreatic cancer, Frontiers in Immunology, 2023.

Follicular lymphoma microenvironment, ASH, 2021.

IL-17 driven inflammatory disease and microbiome, E-Life, 2021.

SARS-CoV2 immunopathology, Cytometry A, 2020.

Immune landscape comparison after Nivolumab and Ipilimumab in melanoma, JCI Insight, 2020.

Molecular cytometry analysis of TIL in lung cancer patients, AAI, 2020.

Kinetics of adult hematopoietic stem cell differentiation in vivo, JEM, 2018.

Genetic architecture of human immune system, Cell, 2015.

Holoendemic malaria and EBV-specific T-cell differentiation, Journal of Virology, 2013.

Immunologic and virologic events in early HIV predict disease progression, JID, 2010.

Size of viral inoculum contributes to Hepatitis B outcome, Journal of Virology, 2009.

High avidity myeloid leukemia-specific T-cells reside preferentially in bone marrow, Blood, 2009.

Founder Pratip Chattopadhyay's Seminal Publications

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